Progress in drug metabolism, volume 1

Abstracts in Persian: Volume 7, Issue 1

Abstracts in Persian, Volume 8, Issue 1

Abstracts in Persian: Volume 6, Issue 1

Progress in Allergy, Volume 23

This book represents the published proceedings of an international symposium on the biochemistry of adenosylmethionine held in Rome, Italy, in 1974. The introductory statement by the editors of this book best illustrates the significance of adenosylmethionine to all branches of biochemistry: "S-adenosylmethionine is probably second only to ATP in the variety of reactions for which it serves as ...

Human carboxylesterase 1: from drug metabolism to drug discovery.

Human carboxylesterase 1 (hCE1) is a serine esterase involved in both drug metabolism and activation, as well as other biological processes. hCE1 catalyses the hydrolysis of heroin and cocaine, and the transesterification of cocaine in the presence of ethanol to the toxic metabolite cocaethylene. We have determined the crystal structures of hCE1 in complex with either the cocaine analogue homat...